《英文msh詞典》c erbB 1 Protein
[入口詞] c erbB 1 Protein
[主題詞] Receptor,Epidermal Growth Factor
[英文釋義] A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA,amphiregulin,and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell.